diff --git a/rpcs3/Emu/CPU/CPUTranslator.h b/rpcs3/Emu/CPU/CPUTranslator.h
index dbae5a5c4e..7d498a7c6d 100644
--- a/rpcs3/Emu/CPU/CPUTranslator.h
+++ b/rpcs3/Emu/CPU/CPUTranslator.h
@@ -30,6 +30,7 @@
 #endif
 
 #include "util/types.hpp"
+#include "util/sysinfo.hpp"
 #include "Utilities/StrFmt.h"
 #include "Utilities/BitField.h"
 #include "Utilities/JIT.h"
@@ -3442,6 +3443,11 @@ public:
 	template <typename T1, typename T2, typename T3>
 	value_t<u8[16]> vperm2b(T1 a, T2 b, T3 c)
 	{
+		if (!utils::has_fast_vperm2b())
+		{
+			return vperm2b256to128(a, b, c);
+		}
+
 		value_t<u8[16]> result;
 
 		const auto data0 = a.eval(m_ir);
diff --git a/rpcs3/Emu/Cell/PPUTranslator.cpp b/rpcs3/Emu/Cell/PPUTranslator.cpp
index e525b0e2fa..8a337c19c4 100644
--- a/rpcs3/Emu/Cell/PPUTranslator.cpp
+++ b/rpcs3/Emu/Cell/PPUTranslator.cpp
@@ -1289,7 +1289,7 @@ void PPUTranslator::VPERM(ppu_opcode_t op)
 	if (m_use_avx512_icl)
 	{
 		const auto i = eval(~c);
-		set_vr(op.vd, vperm2b256to128(b, a, i));
+		set_vr(op.vd, vperm2b(b, a, i));
 		return;
 	}
 
diff --git a/rpcs3/Emu/Cell/SPURecompiler.cpp b/rpcs3/Emu/Cell/SPURecompiler.cpp
index 72149fc591..2802babc95 100644
--- a/rpcs3/Emu/Cell/SPURecompiler.cpp
+++ b/rpcs3/Emu/Cell/SPURecompiler.cpp
@@ -8313,13 +8313,13 @@ public:
 				{
 					if (perm_only)
 					{
-						set_vr(op.rt4, vperm2b256to128(as, bs, c));
+						set_vr(op.rt4, vperm2b(as, bs, c));
 						return;
 					}
 
 					const auto m = gf2p8affineqb(c, build<u8[16]>(0x40, 0x20, 0x20, 0x20, 0x20, 0x20, 0x20, 0x20, 0x40, 0x20, 0x20, 0x20, 0x20, 0x20, 0x20, 0x20), 0x7f);
 					const auto mm = select(noncast<s8[16]>(m) >= 0, splat<u8[16]>(0), m);
-					const auto ab = vperm2b256to128(as, bs, c);
+					const auto ab = vperm2b(as, bs, c);
 					set_vr(op.rt4, select(noncast<s8[16]>(c) >= 0, ab, mm));
 					return;
 				}
@@ -8371,18 +8371,18 @@ public:
 			}
 		}
 
-		if (m_use_avx512_icl && (op.ra != op.rb))
+		if (m_use_avx512_icl && (op.ra != op.rb || m_interp_magn))
 		{
 			if (perm_only)
 			{
-				set_vr(op.rt4, vperm2b256to128(a, b, eval(c ^ 0xf)));
+				set_vr(op.rt4, vperm2b(a, b, eval(c ^ 0xf)));
 				return;
 			}
 
 			const auto m = gf2p8affineqb(c, build<u8[16]>(0x40, 0x20, 0x20, 0x20, 0x20, 0x20, 0x20, 0x20, 0x40, 0x20, 0x20, 0x20, 0x20, 0x20, 0x20, 0x20), 0x7f);
 			const auto mm = select(noncast<s8[16]>(m) >= 0, splat<u8[16]>(0), m);
 			const auto cr = eval(c ^ 0xf);
-			const auto ab = vperm2b256to128(a, b, cr);
+			const auto ab = vperm2b(a, b, cr);
 			set_vr(op.rt4, select(noncast<s8[16]>(c) >= 0, ab, mm));
 			return;
 		}
diff --git a/rpcs3/util/sysinfo.cpp b/rpcs3/util/sysinfo.cpp
index 49ec8e4237..8ee13a2aee 100755
--- a/rpcs3/util/sysinfo.cpp
+++ b/rpcs3/util/sysinfo.cpp
@@ -227,6 +227,19 @@ bool utils::has_fma4()
 #endif
 }
 
+// The Zen4 based CPUs support VPERMI2B/VPERMT2B in a single uop.
+// Current Intel cpus (as of 2022) need 3 uops to execute these instructions.
+// Check for SSE4A (which intel doesn't doesn't support) as well as VBMI.
+bool utils::has_fast_vperm2b()
+{
+#if defined(ARCH_X64)
+	static const bool g_value = has_avx512() && (get_cpuid(7, 0)[2] & 0x2) == 0x2 && get_cpuid(0, 0)[0] >= 0x7 && (get_cpuid(0x80000001, 0)[2] & 0x20) == 0x20;
+	return g_value;
+#else
+	return false;
+#endif
+}
+
 bool utils::has_erms()
 {
 #if defined(ARCH_X64)
diff --git a/rpcs3/util/sysinfo.hpp b/rpcs3/util/sysinfo.hpp
index 110b8bc4f7..23ebefd8e7 100755
--- a/rpcs3/util/sysinfo.hpp
+++ b/rpcs3/util/sysinfo.hpp
@@ -37,6 +37,8 @@ namespace utils
 
 	bool has_fma4();
 
+	bool has_fast_vperm2b();
+
 	bool has_erms();
 
 	bool has_fsrm();