diff --git a/rpcs3/Input/basic_mouse_handler.cpp b/rpcs3/Input/basic_mouse_handler.cpp
index 7bce34beb4..b1b8f54563 100644
--- a/rpcs3/Input/basic_mouse_handler.cpp
+++ b/rpcs3/Input/basic_mouse_handler.cpp
@@ -89,11 +89,23 @@ void basic_mouse_handler::MouseScroll(QWheelEvent* event)
 	MouseHandlerBase::Scroll(event->angleDelta().y());
 }
 
+bool basic_mouse_handler::get_mouse_lock_state()
+{
+	if (m_target)
+	{
+		auto mouse_locked = m_target->property("mouse_locked");
+		if (mouse_locked.isValid())
+			return mouse_locked.toBool();
+		return false;
+	}
+	return false;
+}
+
 void basic_mouse_handler::MouseMove(QMouseEvent* event)
 {
 	if (is_time_for_update())
 	{
-		if (m_target && m_target->visibility() == QWindow::Visibility::FullScreen && m_target->isActive())
+		if (m_target && m_target->isActive() && get_mouse_lock_state())
 		{
 			// get the screen dimensions
 			const QSize screen = m_target->size();
diff --git a/rpcs3/Input/basic_mouse_handler.h b/rpcs3/Input/basic_mouse_handler.h
index f76e520834..06cea8ab24 100644
--- a/rpcs3/Input/basic_mouse_handler.h
+++ b/rpcs3/Input/basic_mouse_handler.h
@@ -24,4 +24,5 @@ public:
 	bool eventFilter(QObject* obj, QEvent* ev) override;
 private:
 	QWindow* m_target = nullptr;
+	bool get_mouse_lock_state();
 };
diff --git a/rpcs3/Input/keyboard_pad_handler.cpp b/rpcs3/Input/keyboard_pad_handler.cpp
index 908a2059e4..3601828f4c 100644
--- a/rpcs3/Input/keyboard_pad_handler.cpp
+++ b/rpcs3/Input/keyboard_pad_handler.cpp
@@ -313,6 +313,18 @@ void keyboard_pad_handler::mouseReleaseEvent(QMouseEvent* event)
 	event->ignore();
 }
 
+bool keyboard_pad_handler::get_mouse_lock_state()
+{
+	if (m_target)
+	{
+		auto mouse_locked = m_target->property("mouse_locked");
+		if (mouse_locked.isValid())
+			return mouse_locked.toBool();
+		return false;
+	}
+	return false;
+}
+
 void keyboard_pad_handler::mouseMoveEvent(QMouseEvent* event)
 {
 	static int movement_x = 0;
@@ -320,7 +332,7 @@ void keyboard_pad_handler::mouseMoveEvent(QMouseEvent* event)
 	static int last_pos_x = 0;
 	static int last_pos_y = 0;
 
-	if (m_target && m_target->visibility() == QWindow::Visibility::FullScreen && m_target->isActive())
+	if (m_target && m_target->isActive() && get_mouse_lock_state())
 	{
 		// get the screen dimensions
 		const QSize screen = m_target->size();
diff --git a/rpcs3/Input/keyboard_pad_handler.h b/rpcs3/Input/keyboard_pad_handler.h
index 2cd7966eb5..656c4a4ed6 100644
--- a/rpcs3/Input/keyboard_pad_handler.h
+++ b/rpcs3/Input/keyboard_pad_handler.h
@@ -101,6 +101,8 @@ protected:
 
 private:
 	QWindow* m_target = nullptr;
+	bool get_mouse_lock_state();
+
 	std::vector<std::shared_ptr<Pad>> bindings;
 
 	// Button Movements
diff --git a/rpcs3/rpcs3qt/gs_frame.cpp b/rpcs3/rpcs3qt/gs_frame.cpp
index 3f6c8bd04e..39b91dbad9 100644
--- a/rpcs3/rpcs3qt/gs_frame.cpp
+++ b/rpcs3/rpcs3qt/gs_frame.cpp
@@ -76,6 +76,11 @@ gs_frame::gs_frame(const QRect& geometry, const QIcon& appIcon, const std::share
 	connect(&m_mousehide_timer, &QTimer::timeout, this, &gs_frame::MouseHideTimeout);
 	m_mousehide_timer.setSingleShot(true);
 
+	// We default the mouse lock to being off
+	m_mouse_hide_and_lock = false;
+	// and we 'publish' this to the property values of this window
+	setProperty("mouse_locked", m_mouse_hide_and_lock);
+
 #ifdef _WIN32
 	m_tb_button = new QWinTaskbarButton();
 	m_tb_progress = m_tb_button->progress();
@@ -135,6 +140,11 @@ void gs_frame::keyPressEvent(QKeyEvent *keyEvent)
 			screenshot.success("Made forced mark %d in log", ++count);
 			return;
 		}
+		else if (keyEvent->modifiers() == Qt::ControlModifier)
+		{
+			toggle_mouselock();
+			return;
+		}
 		break;
 	case Qt::Key_Return:
 		if (keyEvent->modifiers() == Qt::AltModifier)
@@ -209,6 +219,17 @@ void gs_frame::toggle_fullscreen()
 	});
 }
 
+void gs_frame::toggle_mouselock()
+{
+	// first we toggle the value
+	m_mouse_hide_and_lock = !m_mouse_hide_and_lock;
+
+	// and then we publish it to the window properties
+	setProperty("mouse_locked", m_mouse_hide_and_lock);
+
+	HandleCursor(this->visibility());
+}
+
 void gs_frame::close()
 {
 	Emu.Stop();
@@ -465,14 +486,18 @@ void gs_frame::mouseDoubleClickEvent(QMouseEvent* ev)
 
 void gs_frame::HandleCursor(QWindow::Visibility visibility)
 {
-	if (visibility == QWindow::Visibility::FullScreen && !m_show_mouse_in_fullscreen)
+	if (m_mouse_hide_and_lock || (visibility == QWindow::Visibility::FullScreen && !m_show_mouse_in_fullscreen))
 	{
 		setCursor(Qt::BlankCursor);
 		m_mousehide_timer.stop();
 	}
 	else
 	{
-		setCursor(Qt::ArrowCursor);
+		if (!m_mouse_hide_and_lock)
+		{
+			setCursor(Qt::ArrowCursor);
+		}
+
 		if (m_hide_mouse_after_idletime)
 		{
 			m_mousehide_timer.start(m_hide_mouse_idletime);
diff --git a/rpcs3/rpcs3qt/gs_frame.h b/rpcs3/rpcs3qt/gs_frame.h
index aba43e51f4..fd743627a2 100644
--- a/rpcs3/rpcs3qt/gs_frame.h
+++ b/rpcs3/rpcs3qt/gs_frame.h
@@ -36,6 +36,7 @@ private:
 	QString m_window_title;
 	bool m_disable_mouse = false;
 	bool m_disable_kb_hotkeys = false;
+	bool m_mouse_hide_and_lock = false;
 	bool m_show_mouse_in_fullscreen = false;
 	bool m_hide_mouse_after_idletime = false;
 	u32 m_hide_mouse_idletime = 2000; // ms
@@ -77,6 +78,9 @@ protected:
 
 	bool event(QEvent* ev) override;
 
+private:
+	void toggle_mouselock();
+
 private Q_SLOTS:
 	void HandleCursor(QWindow::Visibility visibility);
 	void MouseHideTimeout();