diff --git a/3rdparty/CMakeLists.txt b/3rdparty/CMakeLists.txt
index cb0909e978..dfa73f38e7 100644
--- a/3rdparty/CMakeLists.txt
+++ b/3rdparty/CMakeLists.txt
@@ -193,9 +193,6 @@ if(USE_VULKAN)
 			if (WAYLAND_FOUND)
 				target_include_directories(3rdparty_vulkan
 					INTERFACE ${WAYLAND_INCLUDE_DIR})
-
-				target_compile_definitions(3rdparty_vulkan
-					INTERFACE -DVK_USE_PLATFORM_WAYLAND_KHR)
 			endif()
 		endif()
 
diff --git a/rpcs3/Emu/RSX/VK/VulkanAPI.h b/rpcs3/Emu/RSX/VK/VulkanAPI.h
index b675f9f8fe..c91e9cb5a5 100644
--- a/rpcs3/Emu/RSX/VK/VulkanAPI.h
+++ b/rpcs3/Emu/RSX/VK/VulkanAPI.h
@@ -1,5 +1,6 @@
 #pragma once
 
+// Configure vulkan.h
 #ifdef _WIN32
 #define VK_USE_PLATFORM_WIN32_KHR
 #elif defined(__APPLE__)
@@ -26,6 +27,13 @@
 #pragma warning(pop)
 #endif
 
+// Undefine header configuration variables
+#undef VK_USE_PLATFORM_WIN32_KHR
+#undef VK_USE_PLATFORM_MACOS_MVK
+#undef VK_USE_PLATFORM_ANDROID_KHR
+#undef VK_USE_PLATFORM_XLIB_KHR
+#undef VK_USE_PLATFORM_WAYLAND_KHR
+
 #include <util/types.hpp>
 
 #if VK_HEADER_VERSION < 287